Giant juvenile fibroadenoma in a 12-year-old girl

a case report

Abstract

The Juvenile Giant Fibroadenoma (JGF) is a rare and benign clinical condition that affects young patients between the ages of 10 and 18. Histologically, it is characterized as a circumscribed lesion with rapid proliferation of the stromal and mammary epithelium, which may be associated with genetic mutations. For diagnosis, clinical and histological evaluation of the lesion is necessary to rule out other breast conditions, such as phyllodes tumor. In this case, it concerns a 12-year-old patient with a large lesion in the right breast, which appeared six months prior to the consultation. Ultrasonographic evaluation revealed a solid, hypoechoic mass with well-defined borders, which, along with the biopsy, confirmed the diagnosis of JGF. Given the characteristics of the lesion and its impact on the patient’s life, a surgical approach was chosen, prioritizing the preservation of healthy breast tissue. The excised mass was anatomically analyzed and confirmed the diagnosis of JGF, ruling out other pathologies. Management of this condition requires a personalized approach that considers both the lesion’s and the patient’s characteristics to balance aesthetic concerns with breast health. In the reported case, the surgical approach resulted in a satisfactory outcome, addressing the medical, aesthetic, and psychosocial needs of the patient. This work, therefore, highlights the importance of early diagnosis and the multidisciplinary approach necessary for treating patients with JGF.